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Mismatch repair deficient metastatic colon cancer and urothelial cancer: A case report of sequential immune checkpoint therapy

A major recent advance in cancer therapy involves the use of immune checkpoint therapy for tumors with mismatch repair deficiency, as they have a high tumor mutation load and neoantigen burden. Approximately 4% of advanced colorectal cancer harbors a mismatch repair deficiency. When mismatch repair...

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Dettagli Bibliografici
Pubblicato in:Cancer Biol Ther
Autori principali: Ghatalia, Pooja, Nagarathinam, Rajeswari, Cooper, Harry, Geynisman, Daniel M., El-Deiry, Wafik S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663404/
https://ncbi.nlm.nih.gov/pubmed/28726535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1356506
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