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Lymphangioleiomyomatosis: A Monogenic Model of Malignancy

Lymphangioleiomyomatosis (LAM) is a rare, low-grade, metastasizing neoplasm that arises from an unknown source, spreads via the lymphatics, and targets the lungs. All pulmonary structures become infiltrated with benign-appearing spindle and epithelioid cells (LAM cells) that express smooth-muscle an...

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Detalhes bibliográficos
Publicado no:Annu Rev Med
Main Authors: Krymskaya, Vera P., McCormack, Francis X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663315/
https://ncbi.nlm.nih.gov/pubmed/28099079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-050715-104245
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