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In male rats, the ability of central insulin to suppress glucose production is impaired by olanzapine, whereas glucose uptake is left intact

BACKGROUND: Insulin receptors are widely expressed in the brain and may represent a crossroad between metabolic and cognitive disorders. Although antipsychotics, such as olanzapine, are the cornerstone treatment for schizophrenia, they are associated with high rates of type 2 diabetes and lack effic...

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Detalhes bibliográficos
Publicado no:J Psychiatry Neurosci
Main Authors: Kowalchuk, Chantel, Teo, Celine, Wilson, Virginia, Chintoh, Araba, Lam, Loretta, Agarwal, Sri Mahavir, Giacca, Adria, Remington, Gary J., Hahn, Margaret K.
Formato: Artigo
Idioma:Inglês
Publicado em: Joule Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662464/
https://ncbi.nlm.nih.gov/pubmed/29083297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.170092
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