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Unfolding the chaperone story

Protein folding in the cell was originally assumed to be a spontaneous process, based on Anfinsen’s discovery that purified proteins can fold on their own after removal from denaturant. Consequently cell biologists showed little interest in the protein folding process. This changed only in the mid a...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteur principal: Hartl, F. Ulrich
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662250/
https://ncbi.nlm.nih.gov/pubmed/29084909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0480
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