Novel approach based on one-tube nested PCR and a lateral flow strip for highly sensitive diagnosis of tuberculous meningitis

Rapid and sensitive detection of Mycobacterium tuberculosis (M. Tb) in cerebrospinal fluid is crucial in the diagnosis of tuberculous meningitis (TBM), but conventional diagnostic technologies have limited sensitivity and specificity or are time-consuming. In this work, a novel, highly sensitive mol...

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Bibliographic Details
Published in:PLoS One
Main Authors: Sun, Yajuan, Chen, Jiajun, Li, Jia, Xu, Yawei, Jin, Hui, Xu, Na, Yin, Rui, Hu, Guohua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662171/
https://ncbi.nlm.nih.gov/pubmed/29084241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186985
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