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Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer
BACKGROUND: Doxorubicin is one of the most commonly used chemotherapeutic drugs for breast cancer; however, its use is limited by drug resistance and side-effects. We hypothesized that adding FTY720, a sphingosine-1- phosphate (S1P) receptor functional antagonist, to doxorubicin would potentiate its...
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| Izdano u: | J Surg Res |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661979/ https://ncbi.nlm.nih.gov/pubmed/29078883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2017.05.101 |
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