Frequency and clinical relevance of EGFR mutations and EML4–ALK translocations in octogenarians with non-small cell lung cancer

BACKGROUND: Tyrosine kinase inhibitors (TKIs) have improved response rates in some patients with non-small cell lung cancer (NSCLC), and testing for EGFR mutation and ALK translocation is recommended for all patients with advanced lung adenocarcinoma. The frequency of driver mutations in elderly and...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Tufman, Amanda, Kahnert, Kathrin, Duell, Thomas, Kauffmann-Guerrero, Diego, Milger, Katrin, Schneider, Christian, Stump, Julia, Syunyaeva, Zulfiya, Huber, Rudolf Maria, Reu, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661834/
https://ncbi.nlm.nih.gov/pubmed/29123416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S140472
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