Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems

This article describes our next generation human Liver Acinus MicroPhysiology System (LAMPS). The key demonstration of this study was that Zone 1 and Zone 3 microenvironments can be established by controlling the oxygen tension in individual devices over the range of ca. 3 to 13%. The oxygen tension...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Lee-Montiel, Felipe T, George, Subin M, Gough, Albert H, Sharma, Anup D, Wu, Juanfang, DeBiasio, Richard, Vernetti, Lawrence A, Taylor, D Lansing
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661766/
https://ncbi.nlm.nih.gov/pubmed/28409533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217703978
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