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Facile Synthesis of a Next Generation Safety‐Catch Acid‐Labile Linker, SCAL‐2, Suitable for Solid‐Phase Synthesis, On‐Support Display and for Post‐Synthesis Tagging

The SCAL linker, a safety catch linker, is amongst the most versatile linkers for solid phase synthesis. It was originally described in 1991 by Pátek and Lebl. Yet, its application has been hindered by the low yields of published synthetic routes. Over time, the exceptional versatility of this linke...

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Vydáno v:ChemistrySelect
Hlavní autoři: Portal, Christophe, Hintersteiner, Martin, Barbeau, Olivier, Dodd, Peter, Huggett, Margaret, Pérez‐Pi, Irene, Evans, David, Auer, Manfred
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661701/
https://ncbi.nlm.nih.gov/pubmed/29104911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/slct.201701519
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