Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5

The epithelial-mesenchymal transition (EMT) is a hallmark of cancer metastasis, and the associated molecular signaling pathways are regarded as therapeutic targets for cancer treatment. Thus, suppressing EMT with a natural chemical compound may be of therapeutic benefit. Eupatolide is a natural chem...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Boldbaatar, Ariundavaa, Lee, Sunyi, Han, Sora, Jeong, Ae Lee, Ka, Hye In, Buyanravjikh, Sumiyasuren, Lee, Jeong Hyung, Lim, Jong-Seok, Lee, Myung Sok, Yang, Young
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661662/
https://ncbi.nlm.nih.gov/pubmed/29113242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6957
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