Genetic and environmental factors strongly influence risk, severity and progression of age-related macular degeneration

Age-related macular degeneration (AMD) is characterized by complex interactions between genetic and environmental factors. Here we genotyped the selected 25 single-nucleotide polymorphisms (SNPs) in 983 cases with advanced AMD and 271 cases with intermediate AMD and build an AMD life-risk score mode...

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Udgivet i:Signal Transduct Target Ther
Main Authors: Wang, Wenqiu, Gawlik, Katarzyna, Lopez, Joe, Wen, Cindy, Zhu, Jie, Wu, Frances, Shi, William, Scheibler, Samuel, Cai, Huimin, Vairavan, Ram, Shi, Alexander, Haw, Weldon, Ferreyra, Henry, Zhang, Ming, Chang, Sherman, Zhang, Kang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661646/
https://ncbi.nlm.nih.gov/pubmed/29263899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.16
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