The molecular determinants governing the immunogenicity of Japanese encephalitis live attenuated vaccines

In the course of isolating the attenuated Japanese encephalitis vaccine SA14-14-2, two attenuated strains SA14-9-7 and SA14-5-3 were also obtained that elicited low antibody responses in humans (<10% and 62%, respectively) and exerted much weaker immune protection in animal challenge experiments....

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Gepubliceerd in:Signal Transduct Target Ther
Hoofdauteurs: Li, Yuhua, Fu, Yin, Liu, Xinyu, Yang, Huiqiang, Yu, Yongxin, Jia, Lili, Li, Xuguang, Farnsworth, Aaron, Wang, Junzhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661631/
https://ncbi.nlm.nih.gov/pubmed/29263913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.5
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