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UV-induced damage to DNA: effect of cytosine methylation on pyrimidine dimerization

Methylation/demethylation of cytosine plays an important role in epigenetic signaling, the reversibility of epigenetic modifications offering important opportunities for targeted therapies. Actually, methylated sites have been correlated with mutational hotspots detected in skin cancers. The present...

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Bibliografiske detaljer
Udgivet i:Signal Transduct Target Ther
Main Authors: Martinez-Fernandez, Lara, Banyasz, Akos, Esposito, Luciana, Markovitsi, Dimitra, Improta, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661629/
https://ncbi.nlm.nih.gov/pubmed/29263920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.21
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