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Development of β-cyclodextrin-based hydrogel microparticles for solubility enhancement of rosuvastatin: an in vitro and in vivo evaluation

The aim of this study was to enhance the solubility of rosuvastatin (RST) calcium by developing β-cyclodextrin-g-poly(2-acrylamido-2-methylpropane sulfonic acid [AMPS]) hydrogel microparticles through aqueous free-radical polymerization technique. Prepared hydrogel microparticles were characterized...

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Detalles Bibliográficos
Publicado en:Drug Des Devel Ther
Main Authors: Sarfraz, Rai Muhammad, Ahmad, Mahmood, Mahmood, Asif, Akram, Muhammad Rouf, Abrar, Asad
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661467/
https://ncbi.nlm.nih.gov/pubmed/29123380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S143712
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