Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1

PURPOSE: To evaluate the angiogenic properties of corneal derived mesenchymal stromal cells (Co-MSC). METHODS: Co-MSCs were extracted from human cadaver, and wild-type (C57BL/6J) and SERPINF1(−/−) mice corneas. The MSC secretome was collected in a serum-free medium. Human umbilical vein endothelial...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Eslani, Medi, Putra, Ilham, Shen, Xiang, Hamouie, Judy, Afsharkhamseh, Neda, Besharat, Soroush, Rosenblatt, Mark I., Dana, Reza, Hematti, Peiman, Djalilian, Ali R.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2017
Fag:
Cornea
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661382/
https://ncbi.nlm.nih.gov/pubmed/29075761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22680
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