Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is the most common and aggressive form of brain tumors. GBMs, like other tumors, rely relatively less on mitochondrial oxidative phosphorylation (OXPHOS) and utilize more aerobic glycolysis, and this metabolic shift becomes augmented under hypoxia. In the present study,...

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Veröffentlicht in:Exp Neurobiol
Hauptverfasser: Han, Jiwon Esther, Lim, Pyung Won, Na, Chul Min, Choi, You Sik, Lee, Joo Young, Kim, Yona, Park, Hyung Woo, Moon, Hyo Eun, Heo, Man Seung, Park, Hye Ran, Kim, Dong Gyu, Paek, Sun Ha
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society for Brain and Neural Science 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661062/
https://ncbi.nlm.nih.gov/pubmed/29093638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2017.26.5.295
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