Wnt and Hedgehog Signaling Regulate the Differentiation of F9 Cells into Extraembryonic Endoderm

Mouse F9 cells differentiate into primitive extraembryonic endoderm (PrE) when treated with retinoic acid (RA), and this is accompanied by an up-regulation of Gata6. The role of the GATA6 network in PrE differentiation is known, and we have shown it directly activates Wnt6. Canonical Wnt/β-catenin s...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Deol, Gurjoth S. J., Cuthbert, Tina N., Gatie, Mohamed I., Spice, Danielle M., Hilton, Lindsay R., Kelly, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660979/
https://ncbi.nlm.nih.gov/pubmed/29119099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00093
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