Role of hypocretin/orexin receptor blockade on drug-taking and ultrasonic vocalizations (USVs) associated with low-effort self-administration of cathinone-derived 3,4-methylenedioxypyrovalerone (MDPV) in rats

RATIONALE: Synthetic psychostimulant abuse, including cathinone-derived 3,4-methylenedioxypyrovalerone (MDPV), continues to increase in many countries. Similar to cocaine but with greater potency, MDPV elicits a transient sympathomimetic response by blocking cellular uptake of dopamine (DA) and nore...

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Publicado en:Psychopharmacology (Berl)
Main Authors: Simmons, Steven J., Martorana, Rose, Philogene-Khalid, Helene, Tran, Fionya H., Gentile, Taylor A., Xinyan, Xu, Shu, Su, Rawls, Scott M., Muschamp, John W.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660930/
https://ncbi.nlm.nih.gov/pubmed/28786030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4709-3
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