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Inferring intracellular signal transduction circuitry from molecular perturbation experiments

The development of network inference methodologies that accurately predict connectivity in dysregulated pathways may enable the rational selection of patient therapies. Accurately inferring an intracellular network from data remains a very challenging problem in molecular systems biology. Living cel...

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Bibliographische Detailangaben
Veröffentlicht in:Bull Math Biol
Hauptverfasser: Wynn, Michelle L., Egbert, Megan, Consul, Nikita, Chang, Jungsoo, Wu, Zhi-Fen, Meravjer, Sofia D., Schnell, Santiago
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660674/
https://ncbi.nlm.nih.gov/pubmed/28455685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-017-0270-9
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