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Effect of Polymorphisms at Codon 146 of the Goat PRNP Gene on Susceptibility to Challenge with Classical Scrapie by Different Routes

This report presents the results of experimental challenges of goats with scrapie by both the intracerebral (i.c.) and oral routes, exploring the effects of polymorphisms at codon 146 of the goat PRNP gene on resistance to disease. The results of these studies illustrate that while goats of all geno...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Papasavva-Stylianou, Penelope, Simmons, Marion Mathieson, Ortiz-Pelaez, Angel, Windl, Otto, Spiropoulos, John, Georgiadou, Soteria
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660499/
https://ncbi.nlm.nih.gov/pubmed/28878088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01142-17
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