Effect of Polymorphisms at Codon 146 of the Goat PRNP Gene on Susceptibility to Challenge with Classical Scrapie by Different Routes

This report presents the results of experimental challenges of goats with scrapie by both the intracerebral (i.c.) and oral routes, exploring the effects of polymorphisms at codon 146 of the goat PRNP gene on resistance to disease. The results of these studies illustrate that while goats of all geno...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Papasavva-Stylianou, Penelope, Simmons, Marion Mathieson, Ortiz-Pelaez, Angel, Windl, Otto, Spiropoulos, John, Georgiadou, Soteria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660499/
https://ncbi.nlm.nih.gov/pubmed/28878088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01142-17
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