Mice Deficient in lysophosphatidic acid acyltransferase delta (Lpaatδ)/acylglycerophosphate acyltransferase 4 (Agpat4) Have Impaired Learning and Memory

We previously characterized LPAATδ/AGPAT4 as a mitochondrial lysophosphatidic acid acyltransferase that regulates brain levels of phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI). Here, we report that Lpaatδ(−/−) mice display impaired spatial learning and memory...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Bradley, Ryan M., Mardian, Emily B., Bloemberg, Darin, Aristizabal Henao, Juan J., Mitchell, Andrew S., Marvyn, Phillip M., Moes, Katherine A., Stark, Ken D., Quadrilatero, Joe, Duncan, Robin E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660461/
https://ncbi.nlm.nih.gov/pubmed/28807933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00245-17
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