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WNT-activated bone grafts repair osteonecrotic lesions in aged animals
The Wnt pathway is a new target in bone therapeutic space. WNT proteins are potent stem cell activators and pro-osteogenic agents. Here, we gained insights into the molecular and cellular mechanisms responsible for liposome-reconstituted recombinant human WNT3A protein (L-WNT3A) efficacy to treat os...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660190/ https://ncbi.nlm.nih.gov/pubmed/29079746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14395-9 |
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