Multi-wavelength anomalous diffraction de novo phasing using a two-colour X-ray free-electron laser with wide tunability

Serial femtosecond crystallography at X-ray free-electron lasers (XFELs) offers unprecedented possibilities for macromolecular structure determination of systems prone to radiation damage. However, de novo structure determination, i.e., without prior structural knowledge, is complicated by the inher...

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Published in:Nat Commun
Main Authors: Gorel, Alexander, Motomura, Koji, Fukuzawa, Hironobu, Doak, R. Bruce, Grünbein, Marie Luise, Hilpert, Mario, Inoue, Ichiro, Kloos, Marco, Kovácsová, Gabriela, Nango, Eriko, Nass, Karol, Roome, Christopher M., Shoeman, Robert L., Tanaka, Rie, Tono, Kensuke, Joti, Yasumasa, Yabashi, Makina, Iwata, So, Foucar, Lutz, Ueda, Kiyoshi, Barends, Thomas R. M., Schlichting, Ilme
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660077/
https://ncbi.nlm.nih.gov/pubmed/29079797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00754-7
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