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Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis

BACKGROUND AND PURPOSE: Inflammation plays a key role in atherosclerosis. The protective role of angiotensin 1–7 (Ang‐(1–7)) in vascular pathologies suggested the therapeutic use of low MW, non‐peptide Ang‐(1–7) mimetics, such as AVE0991. The mechanisms underlying the vaso‐protective effects of AVE0...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Skiba, D S, Nosalski, R, Mikolajczyk, T P, Siedlinski, M, Rios, F J, Montezano, A C, Jawien, J, Olszanecki, R, Korbut, R, Czesnikiewicz‐Guzik, M, Touyz, R M, Guzik, T J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659999/
https://ncbi.nlm.nih.gov/pubmed/27935022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13685
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