Chronic Intermittent Hypoxia Worsens Bleomycin-Induced Lung Fibrosis in Rats

Obstructive sleep apnea (OSA) has been linked to increased mortality in pulmonary fibrosis. Its key feature, chronic intermittent hypoxia (CIH), can lead to oxidative stress and inflammation, known to lead to fibrotic pathology in other organs. We tested the effects of CIH in an animal model of bleo...

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Publicado en:Respir Physiol Neurobiol
Main Authors: Braun, Rudolf K., Broytman, Oleg, Braun, Felix M, Brinkman, Jacqueline A., Clithero, Andrew, Modi, Dhruvangkumar, Pegelow, David F., Eldridge, Marlowe, Teodorescu, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659967/
https://ncbi.nlm.nih.gov/pubmed/28456608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2017.04.010
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