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Sertoli Cell Number Defines and Predicts Germ and Leydig Cell Population Sizes in the Adult Mouse Testis

Sertoli cells regulate differentiation and development of the testis and are essential for maintaining adult testis function. To model the effects of dysregulating Sertoli cell number during development or aging, we have used acute diphtheria toxin−mediated cell ablation to reduce Sertoli cell popul...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Rebourcet, Diane, Darbey, Annalucia, Monteiro, Ana, Soffientini, Ugo, Tsai, Yi Ting, Handel, Ian, Pitetti, Jean-Luc, Nef, Serge, Smith, Lee B., O’Shaughnessy, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659676/
https://ncbi.nlm.nih.gov/pubmed/28911170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00196
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