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Optimization of the Small Glycan Presentation for Binding a Tumor-Associated Antibody: Application to the Construction of an Ultrasensitive Glycan Biosensor

The main aim of the study was to optimize the interfacial presentation of a small antigen - a Tn antigen (N-acetylgalactosamine) - for binding to its analyte anti-Tn antibody. Three different methods for the interfacial display of a small glycan are compared here, including two methods based on the...

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Détails bibliographiques
Publié dans:Langmuir
Auteurs principaux: Kveton, Filip, Blšáková, Anna, Hushegyi, Andras, Damborsky, Pavel, Blixt, Ola, Jansson, Bo, Tkac, Jan
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659382/
https://ncbi.nlm.nih.gov/pubmed/28248511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.6b04021
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