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scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing

The interaction between a pathogen and a host is a highly dynamic process in which both agents activate complex programs. Here, we introduce a single-cell RNA-sequencing method, scDual-Seq, that simultaneously captures both host and pathogen transcriptomes. We use it to study the process of infectio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Avital, Gal, Avraham, Roi, Fan, Amy, Hashimshony, Tamar, Hung, Deborah T., Yanai, Itai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658913/
https://ncbi.nlm.nih.gov/pubmed/29073931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1340-x
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