Mast cell chymase promotes hypertrophic scar fibroblast proliferation and collagen synthesis by activating TGF-β1/Smads signaling pathway

The present study assessed the existence of mast cell chymase in hypertrophic scars and determined whether chymase promotes fibrosis via the transforming growth factor (TGF)-β1/Smads signaling pathway. Five patients with hypertrophic scars and another five patients subjected to repair and reconstruc...

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Bibliografske podrobnosti
izdano v:Exp Ther Med
Main Authors: Chen, Hongming, Xu, Yanwen, Yang, Guanbin, Zhang, Qianqian, Huang, Xun, Yu, Liming, Dong, Xianglin
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658735/
https://ncbi.nlm.nih.gov/pubmed/29104654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5082
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