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A 2-base insertion in exon 5 is a common mutation of the TP53 gene in dogs with histiocytic sarcoma

Canine histiocytic sarcoma (HS) is a malignancy originating from the histiocytic cell lineage and characterized by poor response to chemotherapy and short survival time. Mutation of the TP53 gene and its association with poor prognosis has been reported in several canine tumors. However, the mutatio...

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Detalhes bibliográficos
Publicado no:J Vet Med Sci
Main Authors: ASADA, Hajime, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, GOTO-KOSHINO, Yuko, OHNO, Koichi, TSUJIMOTO, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Veterinary Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658567/
https://ncbi.nlm.nih.gov/pubmed/28867679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0197
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