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A 2-base insertion in exon 5 is a common mutation of the TP53 gene in dogs with histiocytic sarcoma

Canine histiocytic sarcoma (HS) is a malignancy originating from the histiocytic cell lineage and characterized by poor response to chemotherapy and short survival time. Mutation of the TP53 gene and its association with poor prognosis has been reported in several canine tumors. However, the mutatio...

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Med Sci
Hauptverfasser: ASADA, Hajime, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, GOTO-KOSHINO, Yuko, OHNO, Koichi, TSUJIMOTO, Hajime
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Veterinary Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658567/
https://ncbi.nlm.nih.gov/pubmed/28867679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0197
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