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Epidermal SIRT1 regulates inflammation, cell migration, and wound healing

Sirtuins (SIRT1-7) are NAD-dependent proteins with the enzymatic activity of deacetylases and ADP ribosyltransferases. SIRT1 is the proto member of the proteins in the mammalian sirtuin family and plays multiple roles in aging and disease. Using mice with epidermis-specific SIRT1 deletion, we show t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qiang, Lei, Sample, Ashley, Liu, Han, Wu, Xiaoyang, He, Yu-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658409/
https://ncbi.nlm.nih.gov/pubmed/29074993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14371-3
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