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Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms
Early-life stress, including maternal separation (MS), increases the vulnerability to develop mood disorders later in life, but the underlying mechanisms remain elusive. We report that MS promotes depressive-like symptoms in mice at a mature stage of life. Along with this behavioral phenotype, MS dr...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658350/ https://ncbi.nlm.nih.gov/pubmed/29074844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01192-1 |
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