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TGF-β Signaling Protects the Thoracic and Abdominal Aorta from Angiotensin II-Induced Pathology by Distinct Mechanisms

OBJECTIVE: The role of TGF-β signaling in abdominal aortic aneurysm (AAA) formation is controversial. Others reported that systemic blockade of TGF-β by neutralizing antibodies accelerated AAA development in angiotensin II-infused mice. This result is consistent with other studies suggesting that TG...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Angelov, Stoyan N., Hu, Jie Hong, Wei, Hao, Airhart, Nathan, Shi, Minghui, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658248/
https://ncbi.nlm.nih.gov/pubmed/28729364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309401
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