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MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance

Understanding the mechanisms of platinum compound resistance, including cisplatin resistance, has important implications for improving cancer treatments. Previous studies identified a potential role for mitogen-activated protein kinase phosphatase-1 (MKP-1) in cisplatin resistance. This work focuses...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Juan, Kho, Dhonghyo, Zhou, Jun-Ying, Davis, Roger J, Wu, Gen Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658239/
https://ncbi.nlm.nih.gov/pubmed/28650468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.197
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