Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy

Targeting of Toxoplasma gondii by autophagy is an effective mechanism by which host cells kill the protozoan. Thus, the parasite must avoid autophagic targeting to survive. Here we show that the mammalian cytoplasmic molecule Focal Adhesion Kinase (FAK) becomes activated during invasion of host cell...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Portillo, Jose-Andres C., Muniz-Feliciano, Luis, Lopez Corcino, Yalitza, Lee, So Jung, Van Grol, Jennifer, Parsons, Sarah J., Schiemman, William P., Subauste, Carlos S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658194/
https://ncbi.nlm.nih.gov/pubmed/29036202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006671
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items