Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy

Targeting of Toxoplasma gondii by autophagy is an effective mechanism by which host cells kill the protozoan. Thus, the parasite must avoid autophagic targeting to survive. Here we show that the mammalian cytoplasmic molecule Focal Adhesion Kinase (FAK) becomes activated during invasion of host cell...

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Publicat a:PLoS Pathog
Autors principals: Portillo, Jose-Andres C., Muniz-Feliciano, Luis, Lopez Corcino, Yalitza, Lee, So Jung, Van Grol, Jennifer, Parsons, Sarah J., Schiemman, William P., Subauste, Carlos S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658194/
https://ncbi.nlm.nih.gov/pubmed/29036202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006671
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