Intrapancreatic injection of human bone marrow-derived mesenchymal stem/stromal cells alleviates hyperglycemia and modulates the macrophage state in streptozotocin-induced type 1 diabetic mice

Type 1 diabetes mellitus is a progressive disease caused by the destruction of pancreatic β-cells, resulting in insulin dependency and hyperglycemia. While transplanted bone marrow-derived mesenchymal stem/stromal cells (BMMSCs) have been explored as an alternative therapeutic approach for diseases,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Murai, Norimitsu, Ohtaki, Hirokazu, Watanabe, Jun, Xu, Zhifang, Sasaki, Shun, Yagura, Kazumichi, Shioda, Seiji, Nagasaka, Shoichiro, Honda, Kazuho, Izumizaki, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657972/
https://ncbi.nlm.nih.gov/pubmed/29073149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186637
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