Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion through Paracrine Factors

Abdominal aortic aneurysm (AAA) is a potentially lethal disease associated with immune activation-induced aortic degradation. We hypothesized that xenotransplantation of human adipose-derived stem cells (hADSCs) would reduce aortic inflammation and attenuate expansion in a murine AAA model. Modulato...

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Bibliographic Details
Published in:Cell Transplant
Main Authors: Xie, Jie, Jones, Thomas J., Feng, Dongni, Cook, Todd G., Jester, Andrea A., Yi, Ru, Jawed, Yameena T., Babbey, Clifford, March, Keith L., Murphy, Michael P.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657756/
https://ncbi.nlm.nih.gov/pubmed/27436185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368916X692212
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