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CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells

In the murine hematopoietic stem cell (HSC) compartment, thrombopoietin (THPO)/MPL (THPO receptor) signaling plays an important role in the maintenance of adult quiescent HSCs. However, the role of THPO/MPL signaling in the human primitive HSC compartment has not yet been elucidated. We have identif...

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Detalhes bibliográficos
Publicado no:Cell Transplant
Main Authors: Matsuoka, Yoshikazu, Takahashi, Masaya, Sumide, Keisuke, Kawamura, Hiroshi, Nakatsuka, Ryusuke, Fujioka, Tatsuya, Sonoda, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657744/
https://ncbi.nlm.nih.gov/pubmed/27938494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368916X694201
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