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Importance of PCR-Based Tumor Testing in the Evaluation of Lynch Syndrome-Associated Endometrial Cancer

Lynch Syndrome is a hereditary cancer syndrome caused by a germline mutation in a DNA mismatch repair gene, usually MLH1, MSH2, MSH6, or PMS2. The most common cancers associated with Lynch Syndrome are colorectal adenocarcinoma and endometrial carcinoma. Identification of women with Lynch Syndrome-a...

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Detalhes bibliográficos
Publicado no:Adv Anat Pathol
Main Authors: Bruegl, Amanda S., Kernberg, Annessa, Broaddus, Russell R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657565/
https://ncbi.nlm.nih.gov/pubmed/28820751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAP.0000000000000169
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