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N (6)-Hydroperoxymethyladenosine: a new intermediate of chemical oxidation of N(6)-methyladenosine mediated by bicarbonate-activated hydrogen peroxide
N (6)-Methyladenosine (m(6)A) represents a relatively abundant modification in eukaryotic RNA. Because m(6)A has similar properties to adenosine and a low reactivity, limited research has been focused on this nucleoside. In this study, we revealed an important intermediate in the oxidation of m(6)A...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Chem Sci |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Royal Society of Chemistry
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657413/ https://ncbi.nlm.nih.gov/pubmed/29142684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00484e |
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