Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity

Renal parenchymal injury predisposes to salt-sensitive hypertension, but how this occurs is not known. Here we tested whether renal tubular angiotensin converting enzyme (ACE), the main site of kidney ACE expression, is central to the development of salt sensitivity in this setting. Two mouse models...

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Publicado en:Kidney Int
Autores principales: Giani, Jorge F., Eriguchi, Masahiro, Bernstein, Ellen A., Katsumata, Makoto, Shen, Xiao Z., Li, Liang, McDonough, Alicia A., Fuchs, Sebastien, Bernstein, Kenneth E., Gonzalez-Villalobos, Romer A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657384/
https://ncbi.nlm.nih.gov/pubmed/27988209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.10.007
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