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Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice

BACKGROUND: Spinal cord injury (SCI) is a devastating disease, which results in tissue loss and neurologic dysfunction. NLRP3 inflammasome plays an important role in the mechanism of diverse diseases. However, no studies have demonstrated the role of NLRP3 inflammasome and the effects of NLRP3 infla...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Jiang, Wu, Li, Maoqiang, He, Fan, Zhou, Shaobo, Zhu, Liulong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657095/
https://ncbi.nlm.nih.gov/pubmed/29070054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0980-9
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