Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination

BACKGROUND: Antibodies to the myelin oligodendrocyte glycoprotein (MOG) are associated with a subset of inflammatory demyelinating diseases of the central nervous system such as acute disseminated encephalomyelitis and neuromyelitis optica spectrum disorders. However, whether human MOG antibodies ar...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Peschl, Patrick, Schanda, Kathrin, Zeka, Bleranda, Given, Katherine, Böhm, Denise, Ruprecht, Klemens, Saiz, Albert, Lutterotti, Andreas, Rostásy, Kevin, Höftberger, Romana, Berger, Thomas, Macklin, Wendy, Lassmann, Hans, Bradl, Monika, Bennett, Jeffrey L., Reindl, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657084/
https://ncbi.nlm.nih.gov/pubmed/29070051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0984-5
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