Cytolytic virus activation therapy and treatment monitoring for Epstein‐Barr virus associated nasopharyngeal carcinoma in a mouse tumor model

Undifferentiated nasopharyngeal carcinoma (NPC) is 100% associated with Epstein‐Barr virus (EBV). Expression of viral proteins in the tumor cells is highly restricted. EBV reactivation by CytoLytic Virus Activation (CLVA) therapy triggers de novo expression of early viral kinases (PK and TK) and use...

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Bibliographic Details
Published in:J Med Virol
Main Authors: Novalić, Zlata, Verkuijlen, Sandra A. W. M., Verlaan, Mariska, Eersels, Jos L. H., de Greeuw, Inge, Molthoff, Carla F. M., Middeldorp, Jaap M., Greijer, Astrid E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656928/
https://ncbi.nlm.nih.gov/pubmed/28853217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.24870
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