Cytolytic virus activation therapy and treatment monitoring for Epstein‐Barr virus associated nasopharyngeal carcinoma in a mouse tumor model

Undifferentiated nasopharyngeal carcinoma (NPC) is 100% associated with Epstein‐Barr virus (EBV). Expression of viral proteins in the tumor cells is highly restricted. EBV reactivation by CytoLytic Virus Activation (CLVA) therapy triggers de novo expression of early viral kinases (PK and TK) and use...

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Publicado en:J Med Virol
Autores principales: Novalić, Zlata, Verkuijlen, Sandra A. W. M., Verlaan, Mariska, Eersels, Jos L. H., de Greeuw, Inge, Molthoff, Carla F. M., Middeldorp, Jaap M., Greijer, Astrid E.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656928/
https://ncbi.nlm.nih.gov/pubmed/28853217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.24870
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