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Pharmacokinetics of Morphine in Rats with Adjuvant-induced Arthritis

We investigated the in vivo dynamics and analgesic effect of morphine using an adjuvant-induced arthritis (AA) rat as a model of chronic inflammation. Morphine generally binds to μ-opioid receptors in the brain to exert its effects. After several minutes, it is metabolized by glucuronidation via a U...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:In Vivo
Asıl Yazarlar: KIMURA, YOSHIAKI, SHIBATA, MIKA, TAMADA, MIKA, OZAKI, NORIYUKI, ARAI, KUNIZO
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Institute of Anticancer Research 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656853/
https://ncbi.nlm.nih.gov/pubmed/28882946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11134
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