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Pharmacokinetics of Morphine in Rats with Adjuvant-induced Arthritis
We investigated the in vivo dynamics and analgesic effect of morphine using an adjuvant-induced arthritis (AA) rat as a model of chronic inflammation. Morphine generally binds to μ-opioid receptors in the brain to exert its effects. After several minutes, it is metabolized by glucuronidation via a U...
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| Publicado no: | In Vivo |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Institute of Anticancer Research
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656853/ https://ncbi.nlm.nih.gov/pubmed/28882946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11134 |
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