miR-204 is associated with an endocrine phenotype in human pancreatic islets but does not regulate the insulin mRNA through MAFA

miR-204 has been proposed to modulate insulin expression in human pancreatic islets by regulating the expression of the MAFA transcript, and in turn insulin transcription. We investigated miR-204 expression in pancreatic endocrine tumors (PET), a panel of human tissues, tissues derived from pancreat...

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Vydáno v:Sci Rep
Hlavní autoři: Marzinotto, Ilaria, Pellegrini, Silvia, Brigatti, Cristina, Nano, Rita, Melzi, Raffaella, Mercalli, Alessia, Liberati, Daniela, Sordi, Valeria, Ferrari, Maurizio, Falconi, Massimo, Doglioni, Claudio, Ravassard, Philippe, Piemonti, Lorenzo, Lampasona, Vito
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656581/
https://ncbi.nlm.nih.gov/pubmed/29070792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13622-7
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