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Cellular splicing factor UAP56 stimulates trimeric NP formation for assembly of functional influenza viral ribonucleoprotein complexes

The influenza virus RNA genome exists as a ribonucleoprotein (RNP) complex by interacting with NP, one of virus-encoded RNA binding proteins. It is proposed that trimeric NP is a functional form, but it is not clear how trimeric NP is formed and transferred to RNA. UAP56, a cellular splicing factor,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, Yifan, Gor, Vishal, Morikawa, Kazuya, Nagata, Kyosuke, Kawaguchi, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656576/
https://ncbi.nlm.nih.gov/pubmed/29070793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13784-4
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