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CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction
Despite its established inter-individual variability, sildenafil has been the subject of only a few pharmacogenetic investigations, with limited data regarding the genetic modulators of its pharmacokinetics. We conducted a pharmacogenetic substudy of patients randomized to sildenafil (n = 85) in the...
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| Publié dans: | Pharmacogenomics J |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656562/ https://ncbi.nlm.nih.gov/pubmed/28440343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2017.8 |
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