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Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence

Nicotine dependence (ND) has a reported heritability of 40–70%. Low-coverage whole-genome sequencing was conducted in 1,889 samples from the UCSF Family study. Linear mixed models were used to conduct genome-wide association tests of ND in this and five cohorts obtained from the database of Genotype...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Yin, Xianyong, Bizon, Chris, Tilson, Jeffrey, Lin, Yuan, Gizer, Ian R., Ehlers, Cindy L., Wilhelmsen, Kirk C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656555/
https://ncbi.nlm.nih.gov/pubmed/28440896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32540
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